Cytotoxicity of diatom-derived oxylipins in organisms belonging to different phyla
نویسندگان
چکیده
منابع مشابه
Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7.
Diatoms are an important class of unicellular algae that produce bioactive secondary metabolites with cytotoxic activity collectively termed oxylipins, including polyunsaturated aldehydes (PUAs), hydroxyacids (HEPEs), oxo-acids and epoxyalcohols. Previous results showed that at higher concentrations, the PUA decadienal induced apoptosis on copepods and sea urchin embryos via caspase-3 activatio...
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Resolution of inflammation has emerged as an active process in immunobiology, with cells of the mononuclear phagocyte system being critical in mediating efferocytosis and wound debridement and bridging the gap between innate and adaptive immunity. Here we investigated the roles of cytochrome P450 (CYP)-derived epoxy-oxylipins in a well-characterized model of sterile resolving peritonitis in the...
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Centro Nacional de Biotecnología-CSIC, Campus Universidad Autónoma, Cantoblanco, E-28049 Madrid, Spain; and 1 Division of Physiological Chemistry II, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden. 2 Present address: Energy Biosciences Institute, University of California, Berkeley, CA 94720, USA. 3 Present address: Syngenta CP, CH-4332 Stein...
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Oxylipins are a large and diverse family of fatty acid derivatives exhibiting different levels of oxidation of the carbon chain. They are involved in many biological functions in mammals, plants and diatoms. In this last group of organisms, they are suggested to play a role in the reproductive failure of copepod predators, showing clear pro-apoptotic effects on newborn nauplii. In this work, th...
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chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2004
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.01105